Citiolone

Chemical compound
  • A05BA04 (WHO)
Identifiers
  • (RS)-N-(2-Oxothiolan-3-yl)acetamide
CAS Number
  • 1195-16-0 checkY
PubChem CID
  • 14520
ChemSpider
  • 13864 checkY
UNII
  • 70JKL15MUH
KEGG
  • D07105 checkY
ChEMBL
  • ChEMBL2104457 ☒N
CompTox Dashboard (EPA)
  • DTXSID0045888 Edit this at Wikidata
ECHA InfoCard100.013.449 Edit this at WikidataChemical and physical dataFormulaC6H9NO2SMolar mass159.20 g·mol−1
InChI
  • InChI=1S/C6H9NO2S/c1-4(8)7-5-2-3-10-6(5)9/h5H,2-3H2,1H3,(H,7,8) checkY
  • Key:NRFJZTXWLKPZAV-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Citiolone is a drug used in liver therapy.

It is a derivative of the amino acid cysteine.[1] Citilone has also been studied with regards to hypothermia due to it being a hydroxyl free radical scavenger. The drug has been shown to protect hamster cells subjected to temperature conditions of 8-25 °C.[2]

References

  1. ^ de Barrio M, Tornero P, Prieto A, Sainza T, Zubeldia JM, Herrero T (1997). "Recurrent fixed drug eruption caused by citiolone". Journal of Investigational Allergology & Clinical Immunology. 7 (3): 193–194. PMID 9252880.
  2. ^ Kruuv J, Glofcheski DJ (June 1993). "Further evidence for two modes of hypothermia damage". Cryobiology. 30 (3): 313–321. doi:10.1006/cryo.1993.1030. PMID 8370318.
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