List of psychoactive substances and precursor chemicals derived from genetically modified organisms

Psychoactive substances

Psychoactive substances derived from genetically modified organisms.

  • Cocaine
    • GMO plant: Nicotiana benthamiana (a tobacco plant)[1]
  • Psilocybin
  • THC
    • GMO bacteria: Zymomonas mobilis (used to produce tequila)[6][7][8]
  • Tropane alkaloids: Hyoscyamine and scopolamine

Precursor chemicals

Precursor chemicals derived from genetically modified organisms.

See also

References

  1. ^ "Genetically modified tobacco plant produces cocaine in its leaves". New Scientist.
  2. ^ Satyanarayana M (7 October 2019). "Modified E. coli pump out psilocybin". Chemical & Engineering News. 97 (39): 11. doi:10.1021/cen-09739-scicon9. S2CID 208747979. Archived from the original on December 3, 2019. Retrieved December 3, 2019.
  3. ^ Technical University of Denmark (2020-04-16). "Psychedelic compound from magic mushrooms produced in yeast". phys.org. Archived from the original on April 30, 2020. Retrieved 2020-05-02.
  4. ^ Milne N (2021-01-15). "Magic Yeasts and How to Make Them Produce Psilocybin". MIND Foundation. Archived from the original on January 15, 2021. Retrieved 2021-01-17.
  5. ^ Wong, G; Lim, LR; Tan, YQ; Go, MK; Bell, DJ; Freemont, PS; Yew, WS (7 February 2022). "Reconstituting the complete biosynthesis of D-lysergic acid in yeast". Nature Communications. 13 (1): 712. Bibcode:2022NatCo..13..712W. doi:10.1038/s41467-022-28386-6. PMC 8821704. PMID 35132076.
  6. ^ "Yeast produce low-cost, high-quality cannabinoids". ScienceDaily.
  7. ^ "German scientists use gene-edited Tequila bacteria to produce cannabinoids". The Drinks Business. 28 March 2019.
  8. ^ Luo X, Reiter MA, d'Espaux L, Wong J, Denby CM, Lechner A, et al. (March 2019). "Complete biosynthesis of cannabinoids and their unnatural analogues in yeast" (PDF). Nature. 567 (7746): 123–26. Bibcode:2019Natur.567..123L. doi:10.1038/s41586-019-0978-9. PMID 30814733. S2CID 71147445.
  9. ^ Srinivasan, Prashanth; Smolke, Christina D. (September 2020). "Biosynthesis of medicinal tropane alkaloids in yeast". Nature. 585 (7826): 614–619. Bibcode:2020Natur.585..614S. doi:10.1038/s41586-020-2650-9. PMC 7529995. PMID 32879484.
  10. ^ "Harvesting baker's yeast for aging-related therapeutics". ScienceDaily.
  11. ^ "Genetically modified E. coli pump out morphine precursor: Bacteria yield 300 times more opiates than yeast". ScienceDaily.
  • v
  • t
  • e
History
BranchesBiological conceptsGeneral conceptsBasic techniques
and tools
Biology field
Chemical field
ApplicationsInterdisciplinary
fieldsLists
  • Category
  • Commons
  • v
  • t
  • e
Major recreational drugs
Depressants
Opioids
Stimulants
Entactogens
Hallucinogens
Psychedelics
Dissociatives
Deliriants
Cannabinoids
Oneirogens
Club drugs
Cannabis culture
Coffee culture
Drinking culture
Psychedelia
Smoking culture
Other
Legality of drug use
International
State level
Drug policy
by country
Drug legality
Other
Other
Drug
production
and trade
Drug
production
Drug trade
Issues with
drug use
Harm reduction
Countries by
drug use
  • v
  • t
  • e
Psychedelics
(5-HT2A
agonists)
Benzofurans
Lyserg‐
amides
Phenethyl‐
amines
2C-x
25x-NBx
25x-NB
25x-NB3OMe
  • 25B-NB3OMe
  • 25C-NB3OMe
  • 25D-NB3OMe
  • 25E-NB3OMe
  • 25H-NB3OMe
  • 25I-NB3OMe
  • 25N-NB3OMe
  • 25P-NB3OMe
  • 25T2-NB3OMe
  • 25T4-NB3OMe
  • 25T7-NB3OMe
  • 25TFM-NB3OMe
25x-NB4OMe
  • 25B-NB4OMe
  • 25C-NB4OMe
  • 25D-NB4OMe
  • 25E-NB4OMe
  • 25H-NB4OMe
  • 25I-NB4OMe
  • 25N-NB4OMe
  • 25P-NB4OMe
  • 25T2-NB4OMe
  • 25T4-NB4OMe
  • 25T7-NB4OMe
  • 25TFM-NB4OMe
25x-NBF
25x-NBMD
  • 25B-NBMD
  • 25C-NBMD
  • 25D-NBMD
  • 25E-NBMD
  • 25F-NBMD
  • 25H-NBMD
  • 25I-NBMD
  • 25P-NBMD
  • 25T2-NBMD
  • 25T7-NBMD
  • 25TFM-NBMD
25x-NBOH
25x-NBOMe
Atypical structures
25x-NMx
  • 25B-NMe7BF
  • 25B-NMe7BT
  • 25B-NMe7Bim
  • 25B-NMe7Box
  • 25B-NMe7DHBF
  • 25B-NMe7Ind
  • 25B-NMe7Indz
  • 25B-NMePyr
  • 25I-NMe7DHBF
  • 25I-NMeFur
  • 25I-NMeTHF
  • 25I-NMeTh
N-(2C)-fentanyl
  • N-(2C-B) fentanyl
  • N-(2C-C) fentanyl
  • N-(2C-D) fentanyl
  • N-(2C-E) fentanyl
  • N-(2C-G) fentanyl
  • N-(2C-H) fentanyl
  • N-(2C-I) fentanyl
  • N-(2C-IP) fentanyl
  • N-(2C-N) fentanyl
  • N-(2C-P) fentanyl
  • N-(2C-T) fentanyl
  • N-(2C-T-2) fentanyl
  • N-(2C-T-4) fentanyl
  • N-(2C-T-7) fentanyl
  • N-(2C-TFM) fentanyl
3C-x
4C-x
DOx
HOT-x
MDxx
Mescaline (subst.)
TMAs
  • TMA
  • TMA-2
  • TMA-3
  • TMA-4
  • TMA-5
  • TMA-6
Others
Piperazines
Tryptamines
alpha-alkyltryptamines
x-DALT
x-DET
x-DiPT
x-DMT
x-DPT
Ibogaine-related
x-MET
x-MiPT
Others
Others
Dissociatives
(NMDAR
antagonists)
Arylcyclo‐
hexylamines
Ketamine-related
PCP-related
Others
Adamantanes
Diarylethylamines
Morphinans
Others
Deliriants
(mAChR
antagonists)
Others
Cannabinoids
(CB1 agonists)
Natural
Synthetic
AM-x
CP x
HU-x
JWH-x
Misc. designer cannabinoids
D2 agonists
GABAA
enhancers
Inhalants
(Mixed MOA)
κOR agonists
Oneirogens
Others