RTI-352
Names | |
---|---|
IUPAC name Methyl 3α-(4-iodophenyl)tropane-2β-carboxylate | |
Systematic IUPAC name Methyl (1R,2S,3R,5S)-3-(4-iodophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate | |
Other names RTI-4229-352 | |
Identifiers | |
CAS Number |
|
3D model (JSmol) |
|
ChemSpider |
|
PubChem CID |
|
UNII |
|
CompTox Dashboard (EPA) |
|
InChI
| |
| |
Properties | |
Chemical formula | C16H20INO2 |
Molar mass | 385.245 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references |
Chemical compound
RTI-352 is a phenyltropane that is used as a radiolabeling ligand for the DAT.[1]
RTI-352 is a geometric isomer of RTI-55 (β-CIT).[2]
Based on X-ray crystallography, this compound is in a tautomeric equilibrium residing mostly on the side of the boat-shaped conformer.
References
- ^ U.S. patent 6,358,492
- ^ Zhan, Yougen; Saindane, Amit M.; Scheffel, Ursula; Carroll, F. Ivy; Holmquist, Christopher R.; Kepler, John A.; Taylor, George F.; Kuhar, Michael J. (1997). "RTI-352: A 3α Analogue of RTI-55 as an in vivo dopamine transporter binding ligand". Synapse. 25 (4): 389–392. doi:10.1002/(SICI)1098-2396(199704)25:4<389::AID-SYN10>3.0.CO;2-Q. PMID 9097398.
- v
- t
- e
Phenyltropanes (classifications)
- PTT/WF-11
- WF-23
- PIT/WF-21
- WF-33
- RTI-352
- RTI-274
- FP-β-CPPIT
- FE-β-CPPIT
- Altropane
- Ioflupane (123I)
This article about an organic compound is a stub. You can help Wikipedia by expanding it. |
- v
- t
- e