ZKSCAN1

Protein-coding gene in the species Homo sapiens
ZKSCAN1
Identifiers
AliasesZKSCAN1, 9130423L19Rik, KOX18, PHZ-37, ZNF139, ZNF36, ZSCAN33, zinc finger with KRAB and SCAN domains 1
External IDsOMIM: 601260; MGI: 1921820; HomoloGene: 34523; GeneCards: ZKSCAN1; OMA:ZKSCAN1 - orthologs
Gene location (Human)
Chromosome 7 (human)
Chr.Chromosome 7 (human)[1]
Chromosome 7 (human)
Genomic location for ZKSCAN1
Genomic location for ZKSCAN1
Band7q22.1Start100,015,572 bp[1]
End100,041,689 bp[1]
Gene location (Mouse)
Chromosome 5 (mouse)
Chr.Chromosome 5 (mouse)[2]
Chromosome 5 (mouse)
Genomic location for ZKSCAN1
Genomic location for ZKSCAN1
Band5|5 G2Start138,083,346 bp[2]
End138,106,084 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • skin of thigh

  • bronchial epithelial cell

  • skin of hip

  • inferior ganglion of vagus nerve

  • external globus pallidus

  • subthalamic nucleus

  • pars reticulata

  • pylorus

  • Pars compacta

  • cardia
Top expressed in
  • medullary collecting duct

  • hand

  • condyle

  • genital tubercle

  • urothelium

  • cumulus cell

  • fossa

  • transitional epithelium of urinary bladder

  • vas deferens

  • renal corpuscle
More reference expression data
BioGPS


More reference expression data
Gene ontology
Molecular function
  • protein binding
  • nucleic acid binding
  • metal ion binding
  • DNA binding
  • DNA-binding transcription factor activity
  • DNA-binding transcription factor activity, RNA polymerase II-specific
Cellular component
  • intracellular anatomical structure
  • nucleus
Biological process
  • regulation of transcription, DNA-templated
  • transcription, DNA-templated
  • regulation of transcription by RNA polymerase II
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

7586

74570

Ensembl

ENSG00000106261

ENSMUSG00000029729

UniProt

P17029

Q8BGS3

RefSeq (mRNA)
NM_001287054
NM_001287055
NM_003439
NM_001346579
NM_001346580

NM_001346581

NM_029869
NM_133906

RefSeq (protein)
NP_001273983
NP_001273984
NP_001333508
NP_001333509
NP_001333510

NP_003430

NP_084145
NP_598667

Location (UCSC)Chr 7: 100.02 – 100.04 MbChr 5: 138.08 – 138.11 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Zinc finger protein with KRAB and SCAN domains 1 is a protein that in humans is encoded by the ZKSCAN1 gene.[5]


See also

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000106261 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000029729 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: ZKSCAN1 zinc finger with KRAB and SCAN domains 1".

Further reading

  • Huebner K, Druck T, Croce CM, Thiesen HJ (1991). "Twenty-seven nonoverlapping zinc finger cDNAs from human T cells map to nine different chromosomes with apparent clustering". Am. J. Hum. Genet. 48 (4): 726–40. PMC 1682948. PMID 2014798.
  • Thiesen HJ (1991). "Multiple genes encoding zinc finger domains are expressed in human T cells". New Biol. 2 (4): 363–74. PMID 2288909.
  • Rousseau-Merck MF, Duro D, Berger R, Thiesen HJ (1995). "Chromosomal localization of two KOX zinc finger genes on chromosome bands 7q21-q22". Ann. Genet. 38 (2): 81–4. PMID 7486829.
  • Tommerup N, Vissing H (1995). "Isolation and fine mapping of 16 novel human zinc finger-encoding cDNAs identify putative candidate genes for developmental and malignant disorders". Genomics. 27 (2): 259–64. doi:10.1006/geno.1995.1040. PMID 7557990.
  • Strausberg RL; Feingold EA; Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Scherer SW; Cheung J; MacDonald JR; et al. (2003). "Human Chromosome 7: DNA Sequence and Biology". Science. 300 (5620): 767–72. Bibcode:2003Sci...300..767S. doi:10.1126/science.1083423. PMC 2882961. PMID 12690205.
  • Jikuya H; Takano J; Kikuno R; et al. (2003). "Characterization of long cDNA clones from human adult spleen. II. The complete sequences of 81 cDNA clones". DNA Res. 10 (1): 49–57. doi:10.1093/dnares/10.1.49. PMID 12693554.
  • Ota T; Suzuki Y; Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Gerhard DS; Wagner L; Feingold EA; et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Olsen JV; Blagoev B; Gnad F; et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.


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