TRPM4 |
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Identifiers |
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Aliases | TRPM4, PFHB1B, TRPM4B, LTrpC4, htransient receptor potential cation channel subfamily M member 4, EKVP6 |
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External IDs | OMIM: 606936; MGI: 1915917; HomoloGene: 23033; GeneCards: TRPM4; OMA:TRPM4 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 19 (human)[1] |
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| Band | 19q13.33 | Start | 49,157,741 bp[1] |
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End | 49,211,836 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 7 (mouse)[2] |
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| Band | 7|7 B3 | Start | 44,952,056 bp[2] |
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End | 44,983,204 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - rectum
- minor salivary glands
- right uterine tube
- skin of abdomen
- gallbladder
- left lobe of thyroid gland
- right lobe of thyroid gland
- ascending aorta
- body of stomach
- right coronary artery
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| Top expressed in | - jejunum
- duodenum
- colon
- ileum
- lip
- left colon
- stomach
- esophagus
- internal carotid artery
- epithelium of stomach
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| More reference expression data |
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BioGPS | | More reference expression data |
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Gene ontology |
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Molecular function | - nucleotide binding
- calcium channel activity
- calmodulin binding
- ion channel activity
- ATP binding
- sodium channel activity
- calcium activated cation channel activity
- calcium ion binding
- metal ion binding
| Cellular component | - integral component of membrane
- Golgi apparatus
- membrane
- plasma membrane
- nucleoplasm
- endoplasmic reticulum
- cytosol
- neuronal cell body
- sodium channel complex
- spanning component of plasma membrane
- spanning component of membrane
| Biological process | - adaptive immune response
- vasoconstriction
- immune system process
- positive regulation of canonical Wnt signaling pathway
- regulation of membrane potential
- cation transport
- ion transport
- protein sumoylation
- dendritic cell chemotaxis
- regulation of T cell cytokine production
- cardiac conduction
- positive regulation of cell population proliferation
- calcium ion transport
- negative regulation of bone mineralization
- positive regulation of atrial cardiac muscle cell action potential
- positive regulation of heart rate
- transmembrane transport
- positive regulation of adipose tissue development
- positive regulation of cytosolic calcium ion concentration
- calcium ion transmembrane transport
- positive regulation of fat cell differentiation
- positive regulation of insulin secretion involved in cellular response to glucose stimulus
- negative regulation of osteoblast differentiation
- positive regulation of vasoconstriction
- positive regulation of regulation of vascular associated smooth muscle cell membrane depolarization
- ion transmembrane transport
- calcium-mediated signaling
- membrane depolarization during AV node cell action potential
- membrane depolarization during Purkinje myocyte cell action potential
- membrane depolarization during bundle of His cell action potential
- regulation of heart rate by cardiac conduction
- sodium ion import across plasma membrane
- regulation of ventricular cardiac muscle cell action potential
- protein homotetramerization
- cellular response to ATP
- inorganic cation transmembrane transport
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | NM_001195227 NM_017636 NM_001321281 NM_001321282 NM_001321283
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NM_001321285 |
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RefSeq (protein) | NP_001182156 NP_001308210 NP_001308211 NP_001308212 NP_001308214
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NP_060106 |
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Location (UCSC) | Chr 19: 49.16 – 49.21 Mb | Chr 7: 44.95 – 44.98 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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