ZNF365

Protein-coding gene in the species Homo sapiens
ZNF365
Identifiers
AliasesZNF365, Su48, UAN, ZNF365D, zinc finger protein 365
External IDsOMIM: 607818; MGI: 2143676; HomoloGene: 8975; GeneCards: ZNF365; OMA:ZNF365 - orthologs
Gene location (Human)
Chromosome 10 (human)
Chr.Chromosome 10 (human)[1]
Chromosome 10 (human)
Genomic location for ZNF365
Genomic location for ZNF365
Band10q21.2Start62,374,192 bp[1]
End62,480,288 bp[1]
Gene location (Mouse)
Chromosome 10 (mouse)
Chr.Chromosome 10 (mouse)[2]
Chromosome 10 (mouse)
Genomic location for ZNF365
Genomic location for ZNF365
Band10|10 B5.1Start67,721,933 bp[2]
End67,748,492 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • middle temporal gyrus

  • Brodmann area 23

  • postcentral gyrus

  • superior frontal gyrus

  • Brodmann area 46

  • Brodmann area 10

  • orbitofrontal cortex

  • frontal pole

  • occipital lobe

  • endothelial cell
Top expressed in
  • piriform cortex

  • Region I of hippocampus proper

  • prefrontal cortex

  • primary motor cortex

  • olfactory tubercle

  • subiculum

  • amygdala

  • visual cortex

  • superior frontal gyrus

  • globus pallidus
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
  • protein homodimerization activity
  • protein binding
  • identical protein binding
  • metal ion binding
Cellular component
  • gamma-tubulin complex
  • centrosome
  • cytoplasm
  • cytoskeleton
  • microtubule organizing center
  • intracellular membrane-bounded organelle
Biological process
  • gamma-tubulin complex localization
  • mitotic cytokinesis
  • telomere maintenance
  • regulation of double-strand break repair via homologous recombination
  • negative regulation of neuron projection development
  • cerebellar molecular layer morphogenesis
  • positive regulation of oligodendrocyte differentiation
  • dendritic spine morphogenesis
  • regulation of DNA strand resection involved in replication fork processing
  • dendrite arborization
  • nervous system development
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

22891

216049

Ensembl

ENSG00000138311

ENSMUSG00000037855

UniProt

Q70YC4
Q70YC5

Q8BG89

RefSeq (mRNA)

NM_014951
NM_199450
NM_199451
NM_199452

NM_178679

RefSeq (protein)
NP_055766
NP_955522
NP_955523
NP_055766.2
NP_955522.1

NP_955523.1

NP_848794

Location (UCSC)Chr 10: 62.37 – 62.48 MbChr 10: 67.72 – 67.75 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Protein ZNF365 is a protein that in humans is encoded by the ZNF365 gene.[5][6][7]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000138311 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000037855 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Nagase T, Ishikawa K, Suyama M, Kikuno R, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Dec 1998). "Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Research. 5 (6): 355–64. doi:10.1093/dnares/5.6.355. PMID 10048485.
  6. ^ Gianfrancesco F, Esposito T, Ombra MN, Forabosco P, Maninchedda G, Fattorini M, Casula S, Vaccargiu S, Casu G, Cardia F, Deiana I, Melis P, Falchi M, Pirastu M (Jun 2003). "Identification of a novel gene and a common variant associated with uric acid nephrolithiasis in a Sardinian genetic isolate". American Journal of Human Genetics. 72 (6): 1479–91. doi:10.1086/375628. PMC 1180308. PMID 12740763.
  7. ^ "Entrez Gene: ZNF365 zinc finger protein 365".

Further reading

  • Ombra MN, Forabosco P, Casula S, Angius A, Maestrale G, Petretto E, Casu G, Colussi G, Usai E, Melis P, Pirastu M (May 2001). "Identification of a new candidate locus for uric acid nephrolithiasis". American Journal of Human Genetics. 68 (5): 1119–29. doi:10.1086/320105. PMC 1226093. PMID 11309680.
  • Gianfrancesco F, Esposito T, Casu G, Maninchedda G, Roberto R, Pirastu M (Sep 2004). "Emergence of Talanin protein associated with human uric acid nephrolithiasis in the Hominidae lineage". Gene. 339: 131–8. doi:10.1016/j.gene.2004.06.030. PMID 15363853.
  • Wang Q, Du X, Meinkoth J, Hirohashi Y, Zhang H, Liu Q, Richter M, Greene MI (Apr 2006). "Characterization of Su48, a centrosome protein essential for cell division". Proceedings of the National Academy of Sciences of the United States of America. 103 (17): 6512–7. Bibcode:2006PNAS..103.6512W. doi:10.1073/pnas.0601682103. PMC 1458915. PMID 16617106.
  • Hirohashi Y, Wang Q, Liu Q, Li B, Du X, Zhang H, Furuuchi K, Masuda K, Sato N, Greene MI (Oct 2006). "Centrosomal proteins Nde1 and Su48 form a complex regulated by phosphorylation". Oncogene. 25 (45): 6048–55. doi:10.1038/sj.onc.1209637. PMID 16682949. S2CID 25669587.

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


  • v
  • t
  • e
(1) Basic domains
(1.1) Basic leucine zipper (bZIP)
(1.2) Basic helix-loop-helix (bHLH)
Group A
Group B
Group C
bHLH-PAS
Group D
Group E
Group F
bHLH-COE
(1.3) bHLH-ZIP
(1.4) NF-1
(1.5) RF-X
(1.6) Basic helix-span-helix (bHSH)
(2) Zinc finger DNA-binding domains
(2.1) Nuclear receptor (Cys4)
subfamily 1
subfamily 2
subfamily 3
subfamily 4
subfamily 5
subfamily 6
subfamily 0
(2.2) Other Cys4
(2.3) Cys2His2
(2.4) Cys6
(2.5) Alternating composition
(2.6) WRKY
(3) Helix-turn-helix domains
(3.1) Homeodomain
Antennapedia
ANTP class
protoHOX
Hox-like
metaHOX
NK-like
other
(3.2) Paired box
(3.3) Fork head / winged helix
(3.4) Heat shock factors
(3.5) Tryptophan clusters
(3.6) TEA domain
  • transcriptional enhancer factor
(4) β-Scaffold factors with minor groove contacts
(4.1) Rel homology region
(4.2) STAT
(4.3) p53-like
(4.4) MADS box
(4.6) TATA-binding proteins
(4.7) High-mobility group
(4.9) Grainyhead
(4.10) Cold-shock domain
(4.11) Runt
(0) Other transcription factors
(0.2) HMGI(Y)
(0.3) Pocket domain
(0.5) AP-2/EREBP-related factors
(0.6) Miscellaneous
see also transcription factor/coregulator deficiencies


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